CP-Chirasil

CP-Chirasil (Chrompack) GC Column from Agilent Technologies

Agilent J&W CP-Chirasil Val columns are designed for the separation of optically active compounds, especially amino acids. They have lower bleed levels than other phases with a Tmax of 200 °C, isothermally and programmed. Both antipodes of the phase are available. On Chirasil-L-Val, D-amino acids elute before the L-amino acids, while on Chirasil-D-Val this elution order is reversed. This is especially valuable when determining the optical purity of compounds. Selecting the column from which the minor component elutes before the major enantiomer results in the lowest detection levels.

Agilent J&W CP-Chirasil-Dex CB consists of cyclodextrin directly bonded to dimethylpolysiloxane. This bond prevents the cyclodextrin from migrating to different locations in the surface film, delivering homogeneous enantioselectivity throughout the phase, which provides the highest resolution factor between isomers. It also guarantees stability of enantioselectivity. As a result, the lifetime of β-cyclodextrin capillary columns is significantly improved. CP-Chirasil-Dex CB permits low elution temperatures of polar compounds and is suitable for all injection techniques.

CP-Chirasil All pictures shown are for illustration purpose only. Actual product may vary.

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Features

CP-Chirasil Val GC Columns

Agilent J&W CP-Chirasil Val columns are designed for the separation of optically active compounds, especially amino acids.

Designed for separations of optically active compounds including amino acids
Both antipode phases available (D and L) for maximum versatility
Stabilized phase, over 50% cross linked for great longevity
Specially designed and tested for amino acid enantiomers for the ultimate in reliable data
Low Bleed
Note: On Chirasil-L Val, D-amino acids elute before the L-amino acids, while on Chirasil-D-Val, this elution order is reversed. This is especially valuable when determining the optical purity of these compounds. Selecting the column from which the minor compound elutes before the major enantiomers results in the lowest detection levels.

CP-Chirasil-Dex CB GC Columns

Agilent J&W The CP-Chirasil-Dex CB phase has the highest resolution factor between isomers with guaranteed enantioselective stability for improved lifetime.

Cyclodextrin bonded to dimethylpolysiloxane for homogeneous enantioselectivity throughout the column
High resolution factor between isomers across a broad application range
Chemically-bonded phase for excellent longevity
No need for derivatization improves productivity
Low elution temperature of polar compounds
Suitable for all injection techniques

Similar Phases: LIPODEX C, Rt-β DEXm, β-DEX 110, β-DEX 120

Specifications

CP-Chirasil Val Temperature Specifications

ID (mm)	0.25 mm
Length (m)	25 m
Film (µm)	0.08 – 0.12 µm
Temperature Limits (°C)	200/200 °C

CP-Chirasil-Dex CB Temperature Specifications

ID (mm)	0.25 – 0.32 mm
Length (m)	25 m
Film (µm)	0.25 µm
Temperature Limits (°C)	200/200 °C

Literature

Agilent GC Column Brochure

Full range of Agilent Technologies GC columns and applications